a) Derek/Jesse/Riley, and all the entanglements thereof. It's such a complicated and fascinating relationship. Sarah/Ellison, actually. Their interactions are pretty much always interesting, and I feel like they could be good for each other. And I feel like I should put John/Cameron here, but I also want to put Sarah/Jesse, but Jesse/Lauren is totally edging them both out. :D THE POTENTIAL.
b) Derek/Cameron. So, so interesting. Ellison/John. It could have been so good. Cameron/Catherine Weaver. That would have been so awesome. *sigh*
c) Cameron/Catherine Weaver OR Sarah/Jesse OR Jesse/Lauren.